Home Antibody All anti-PSMA2 antibodies
Also for PSMA2 (NM_002787)
|Recombinant fragment corresponding to a region within amino acids 1 and 234 of Proteasome 20S alpha 2 (Uniprot ID#P25787)|
|Human (Predicted: Mouse, Rat, Rhesus Monkey, Bovine)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%)
|Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2)|
|HC3; MU; PMSA2; PSC2|
Entrez Gene 5683 Human
Entrez Gene 19166 Mouse
Entrez Gene 29669 Rat
Entrez Gene 701683 Monkey
|The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. [provided by RefSeq]|
|ProteaseDruggable Genome Proteasome|
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Sample(30ug of whole cell lysate). A: H1299. B: HeLa S3 . C: Hep G2 . D: MOLT4 . E: Raji . 12% SDS PAGE. TA308489 diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded CA922 xenograft, using Proteasome 20S alpha 2(TA308489) antibody at 1:500 dilution.
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using 20S Proteasome alpha2(TA308489) antibody at 1:200 dilution.