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Anti-PSMA1 Antibody EPR5452
Also for PSMA1 (NM_001143937)
|A synthetic peptide corresponding to residues on the C-terminus in human PSMA1 was used as an immunogen|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:250 - 1:500; FC: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Homo sapiens proteasome (prosome, macropain) subunit, alpha type, 1 (PSMA1), transcript variant 3|
|HC2; NU; PROS30|
|The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA1 is a member of the peptidase T1A family, that is a 20S core alpha subunit (1).|
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Western blot - Proteasome 20S C2 antibody [EPR5452]; All lanes : Anti-Proteasome 20S C2 antibody [EPR5452] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : PC3 cell lysates.Lysates/proteins at 10 µg per lane.Predicted band size : 30 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Proteasome 20S C2 antibody [EPR5452]; ab109530, at 1/100 dilution, staining Proteasome 20S C2 in paraffin embedded Human medullary carcinoma tissue by Immunohistochemistry.