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Home Antibody All anti-PRSS12 antibodies

Anti-PRSS12 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306416
  • Rabbit Polyclonal Neurotrypsin Antibody
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for PRSS12 (NM_003619)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenNeurotrypsin antibody was raised against a 23 amino acid peptide from near the amino terminus of human neurotrypsin.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens protease, serine, 12 (neurotrypsin, motopsin) (PRSS12)
Alternative NameBSSP-3; BSSP3; MRT1
Database LinkNP_003610
Entrez Gene 8492 Human
Entrez Gene 19142 Mouse
Entrez Gene 85266 Rat
FunctionNeurotrypsin is a central nervous system-expressed serine protease whose truncation or absence causes nonsyndromic mental retardation. It is most prominently expressed in structures that are involved in the processing and storage of learned behavior and memory, such as the cerebral cortex, the hippocampus, and amygdala. Evidence suggests that neurotrypsin has multiple functions, including axonal outgrowth, maintaining neuronal plasticity, and arranging the perineuronal environment, partly in coordination with other proteases including tissue plasminogen activator. At least two isoforms of neurotrypsin are known to exist.
Related PathwaySecreted ProteinProteaseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of neurotrypsin in SK-N-SH cell lysate with neurotrypsin antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.
IHC Image
Immunohistochemistry of Neurotrypsin in human brain tissue with Neurotrypsin antibody at 2.5 ug/ml.

 

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