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Home Antibody All anti-PRNP antibodies

Anti-PRNP Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302683
  • Goat Polyclonal Antibody against Prion Protein (143-153)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC403657) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence C-SDYEDRYYREN, from the internal region of the protein sequence according to NP_000302.1; NP_898902.1.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse, Rat, Dog, etc Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB: 0.3-1µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens prion protein (PRNP), transcript variant 2
Alternative NameAltPrP; ASCR; CD230; CJD; GSS; KURU; p27-30; PRIP; PrP; PrP27-30; PrP33-35C; PrPc
Database LinkNP_898902
FunctionThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq].
Related Pathway

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WB Image
TA302683 (0.3µg/ml) staining of Human Brain lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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