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Home Antibody All anti-PRL antibodies

Anti-PRL Antibody EPR3216

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307656
  • Rabbit monoclonal antibody against Prolactin (clone EPR3216 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424443) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for PRL (NM_000948)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Prolactin was used as an immunogen.
Clone NameEPR3216 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:20000 - 1:100000
BufferDoes not react with Mouse, Rat. Is unsuitable for ICC/IF,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens prolactin (PRL), transcript variant 1
Alternative NameOTTHUMP00000017727; Prolactin
Database LinkNP_000939
Entrez Gene 5617 Human
FunctionProlactin (PRL) is a peptide hormone secreted from the anterior pituitary gland, primarily associated with lactation. It plays an important role in the proliferation and differentiation of cells in mammary gland development (1, 2). It also participates in regulation of angiogenesis (3). PRL has more actions than all other pituitary hormones combined. The initial step in the action of PRL, like all other hormones, is the binding to a specific membrane receptor, the PRL receptor (PRLR). Pituitary PRL acts via a classic endocrine pathway (2). The PRL that is produced by many different cell types can act in a more direct fashion; i.e., as a growth factor, neurotransmitter or immunomodulator, in an autocrine or paracrine manner. Thus, locally produced PRL can act on adjacent cells (paracrine) or on the PRL-secreting cell itself (autocrine) in many tissues via the broad distribution of its receptors (2, 4).
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionNeuroactive ligand-receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Prolactin antibody [EPR3216]; All lanes : Anti-Prolactin antibody [EPR3216] at 1/50000 dilution.Lane 1 : Prolactin recombinant protein .Lane 2 : Human fetal pituitary lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 26 kDa.

 

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