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Home All anti-PRKDC antibodies
Anti-PRKDC Phospho Antibody EPR2251
TrueMAB™ Antibodies - Made against Authentic Protein Antigens
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for PRKDC (NM_001081640)
OriGene Data
| A phospho specific peptide corresponding to residues surrounding serine 2612 of human DNA-PK/PRKDC was used as an immunogen. This antibody only detects DNA-PK/PRKDC phosphorylated at serine 2612. |
| EPR2251 |
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| Human |
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| WB |
WB: 1:1,000 - 10,000; IHC 1:100 - 250; ICC: 1:100 - 250; |
| Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. |
| (Protein A or G Sepharose) |
Reference Data
| Homo sapiens protein kinase, DNA-activated, catalytic polypeptide (PRKDC), transcript variant 2 |
| DNA-PKcs; DNAPK; DNPK1; HYRC; HYRC1; p350; XRCC7 |
| NP_001075109 |
| DNA-PK/PRKDC, the catalytic subunit of the DNA-dependent protein kinase, is a member of the PI3/PI4-kinase family. It functions with the Ku70/Ku80 heterodimer protein in DNA double strand break repair and recombination (1). Autophosphorylation of DNA-PK correlates with loss of protein kinase activity and dissociation of the DNA-PKcs-Ku complex. DNA-PK phosphorylates Hsp90, p53 and c-Jun (2,3). |
Cell cycle |
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
WB Image
Western blot analysis on LnCaP cell lysates using anti-Phospho-DNA-PK/PRKDC (pS2612) RabMAb. Cells were either (A,C) untreated or (B,D) treated with alkaline phosphatase (AP).<br>Lane C and D were probed using pan DNA-PK/PRKDC RabMAb
Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:
- HRP
- Biotin
- PE
- FITC
- DyLight® 488
- DyLight® 550
- DyLight® 594
- DyLight® 633
* DyLight is a trademark of Thermo-Fisher Scientific
Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.
Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)
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