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Home Antibody All anti-PRKCE antibodies

Anti-PRKCE Antibody EPR1482(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA311042
  • Rabbit Monoclonal antibody against PKC Epsilon (PRKCE)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401658) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for PRKCE (NM_005400)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PKC Epsilon was used as an immunogen.
Clone NameEPR1482(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IHC-P: 1:100 - 1:250; FC: 1:100 - 1:500; ICC/IF: 1:50 - 1:100
Predicted MW Explanation 84 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens protein kinase C, epsilon (PRKCE)
Alternative NamenPKC-epsilon; PKCE
Database LinkNP_005391
Entrez Gene 5581 Human
Entrez Gene 18754 Mouse
Entrez Gene 29340 Rat
FunctionProtein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC Epsilon is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior (1).
Related PathwayProtein KinaseDruggable Genome Vascular smooth muscle contractionTight junctionFc epsilon RI signaling pathwayFc gamma R-mediated phagocytosisType II diabetes mellitus

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PKC epsilon antibody [EPR1482(2)]; All lanes : Anti-PKC epsilon antibody [EPR1482(2)] at 1/10000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : MCF7 cell lysate.Lane 3 : HT29 cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 84 kDa.Observed band size : 82 kDa .
Assay Image
Other-Anti-PKC epsilon antibody [EPR1482(2)](TA311042); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PKC epsilon antibody [EPR1482(2)]; TA311042, at 1/100 dilution, staining PKC epsilon in paraffin-embedded Human kidney tissue by Immunohistochemistry.

 

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