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Home Antibody All anti-PRKAR2A antibodies

Anti-PRKAR2A TRUEMAB Antibody clone 1G7

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA501104
  • anti-PRKAR2A (PKA R2 ) mouse monoclonal antibody, clone 1G7
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401337) , 20ug
100ul 325 In Stock
CF501104
  • Carrier-free (BSA/glycerol-free) PRKAR2A mouse monoclonal antibody, clone 1G7
100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(1)
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Also for PRKAR2A (NM_004157)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PRKAR2A (NP_004148) produced in HEK293T cell.
Clone Nameclone 1G7 IsotypeIgG1
Species ReactivityHuman Concentration0.74 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:1000, IHC 1:50, IF 1:100,
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A)
Alternative NamePKR2; PRKAR2
Database LinkNP_004148
FunctioncAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER).
Related Pathway
TGF Beta Signaling Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PRKAR2A (RC220376, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PRKAR2A.
IHC Image
Immunohistochemical staining of paraffin-embedded prostate tissue using anti-PRKAR2A mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA501104, Dilution 1:50)
IF Image
Anti-PRKAR2A mouse monoclonal antibody (TA501104) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PRKAR2A(RC220376).

 

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