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Home Antibody All anti-PRKAR2A antibodies

Anti-PRKAR2A Antibody Y116

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300466
  • Rabbit Monoclonal Antibody against PRKAR2A (Clone Y116)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401337) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for PRKAR2A (NM_004157)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-terminus of human cAMP-dependent protein kinase type II-alpha regulatory subunit was used as immunogen. The antibody does not cross-react with other cAMP-dependent kinase.
Clone NameY116 IsotypeIgG
Species ReactivityHuman, Mouse ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:500~1000; IHC: 1: 100-250; ICC: 1: 100-250; IP: 1:50
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens protein kinase, cAMP-dependent, regulatory, type II, alpha (PRKAR2A)
Alternative NamePKR2; PRKAR2
Database LinkNP_004148
FunctionPKA (or cAPK) is a cyclic AMP-dependent protein kinase. When activated by the second messenger cAMP, PKA mediates diverse cellular mechanisms, including proliferation, ion transport, regulation of metabolism, and gene transcription (1,2). PKA is comprised of two dimers of two subunits, R (regulatory) and C (catalytic). Two families of R subunits (RI and RII) have been identified, each possessing distinct cAMP binding properties and resulting in different phosphorylation states (2,3).
Related Pathway
TGF Beta Signaling Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PKA R2 antibody [Y116]; Anti-PKA R2 antibody [Y116] at 1/50000 dilution + K562 cell lysate .Predicted band size : 45 kDa.Observed band size : 52 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - PKA R2 antibody [Y116]; Immunohistochemical analysis of paraffin-embedded human normal breast tissue using TA300466 at 1/100 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - PKA R2 antibody [Y116]; Immunofluorescent staining of HeLa cells using TA300466 at 1/100 dilution.

 

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