Home Antibody All anti-PRKACA antibodies
Also for PRKACA (NM_002730)
|Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 340 of PRKACA|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
|Homo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), transcript variant 1|
|cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]|
Hedgehog signaling pathway
MAPK signaling pathway
Wnt Signaling Pathway
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Sample(30 ug of whole cell lysate) A:HeLa S3 (anti-PRKACA antibody diluted at 1:500)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using PRKACA(anti-PRKACA antibody) antibody at 1:200 dilution.