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Home Antibody All anti-PRKACA antibodies

Anti-PRKACA Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308159 Rabbit polyclonal antibody to PRKACA (protein kinase, cAMP-dependent, catalytic, alpha) 100ul $325 3-7 Days
LC419140 PRKACA HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for PRKACA (NM_002730)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 351 of PKA C alpha (Uniprot ID#P17612)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 41kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens protein kinase, cAMP-dependent, catalytic, alpha (PRKACA), transcript variant 1
Alternative NamePKACA; PPNAD4
Database LinkNP_002721
Entrez Gene 5566 Human
Entrez Gene 18747 Mouse
FunctioncAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayCalcium signaling pathwayChemokine signaling pathwayOocyte meiosisApoptosisVascular smooth muscle contractionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: NIH-3T3. B: C2C12. 10% SDS PAGE. TA308159 diluted at 1:1000.

WB Image
Sample(30 ug of whole cell lysate). A:HeLa S3. 12% SDS PAGE. TA308159 diluted at 1:500

IF Image
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using PKA alpha(TA308159) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.


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