Home All anti-PRKAA2 antibodies
Anti-PRKAA2 Phospho Antibody EPR3052
* Buy one primary antibody, get 50% off a GAPDH loading control antibody.
Also for PRKAA2 (NM_006252)
|A phospho specific peptide corresponding to residues surrounding Serine 491 of human AMPK alpha 2 was used as an immunogen. This antibody only detects AMPK alpha 2 phosphorylated at Serine 491.|
|Human, Mouse, Rat
||WB: 1:1,000 - 10,000,
|Store at -20 C. Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.|
|Homo sapiens protein kinase, AMP-activated, alpha 2 catalytic subunit (PRKAA2)|
|AMPK; AMPK2; AMPKa2; PRKAA|
|AMPK alpha 2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.|
* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Western blot analysis on 293T cell lysates using anti-Phospho-AMPK alpha 2 (pS491) RabMAb .