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Home Antibody All anti-PRDX6 antibodies

Anti-PRDX6 Antibody EPR3754

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307266 Rabbit monoclonal antibody against Peroxiredoxin 6(clone EPR3754) 100ul $325 In Stock
LC401530 PRDX6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(5)
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Also for PRDX6 (NM_004905)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues of human Peroxiredoxin 6 was used as an immunogen
Clone NameEPR3754 IsotypeIgG
Species ReactivityMouse, Rat, Human, Pig ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsICC/IF: 1:100 - 1:250; WB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; FC: 1:500 - 1:1000
Predicted MW Explanation 25 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IP.

Reference Data

Target NameHomo sapiens peroxiredoxin 6 (PRDX6)
Alternative Name1-Cys; aiPLA2; AOP2; HEL-S-128m; NSGPx; p29; PRX
Database LinkNP_004896
Entrez Gene 9588 Human
Entrez Gene 11758 Mouse
Entrez Gene 94167 Rat
FunctionPeroxiredoxins (Prx) are a family of ubiquitous antioxidant enzymes which regulates cytokine-induced peroxide levels and mediates signal transduction in various mammalian cells. Prx family members have been linked to cell proliferation, differentiation, and apoptosis (1). Peroxiredoxin 6 (Prdx6) is only mammalian 1-Cys member of the peroxiredoxin family and it is expressed in all major organs, with particularly high expression in lung. Prdx6 is considered antioxidant enzyme and has a major role in lung phospholipid metabolism. Specifically, Prdx6 might be involved in antioxidant defense by facilitating repair of damaged cell membranes via reduction of peroxidized phospholipids and alterations of lung surfactant phospholipid synthesis and turnover (2).
Related PathwayDruggable Genome Phenylalanine metabolismMethane metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-Peroxiredoxin 6 antibody [EPR3754]; All lanes : Anti-Peroxiredoxin 6 antibody [EPR3754].Lane 1 : HeLa lysate.Lane 2 : 293 lysate.Lane 3 : Fetal liver lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 25 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Peroxiredoxin 6 antibody [EPR3754]; Immunohistochemical analysis of paraffin-embedded Human brain tissue labelling Peroxiredoxin 6 with TA307266 at 1/250 dilution.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3754](TA307266); Immunohistochemical analysis of paraffin embedded normal Human liver tissue using TA307266 showing +ve staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3754](TA307266); Immunohistochemical analysis of paraffin embedded normal Human placenta tissue using TA307266 showing +ve staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3754](TA307266); Immunohistochemical analysis of paraffin embedded normal Human stomach tissue using TA307266 showing +ve staining.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Peroxiredoxin 6 antibody [EPR3754](TA307266); Immunohistochemical analysis of paraffin embedded normal Human testis tissue using TA307266 showing +ve staining.
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