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Home Antibody All anti-PPP6C antibodies

Anti-PPP6C Antibody EPR8764

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310774
  • Rabbit Monoclonal antibody against PPP6C
  • FREE positive control: HEK293T cell transient overexpression lysate (LC426607) , 20ug
100ul 325 3-7 Days
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WB(1)
IF(1)
Assay(1)
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Also for PPP6C (NM_001123355)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human PPP6C was used as an immunogen.
Clone NameEPR8764 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens protein phosphatase 6, catalytic subunit (PPP6C), transcript variant 1
Alternative NamePP6; PP6C
Database LinkNP_001116827
FunctionPPP6C is the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PPP6C restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PPP6C also downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7 (1).
Related Pathway

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WB Image
Western blot - Anti-PPP6C antibody [EPR8764]; All lanes : Anti-PPP6C antibody [EPR8764] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Fetal thymus lysate.Lane 3 : 293T cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 35 kDa.
Assay Image
Other-Anti-PPP6C antibody [EPR8764](TA310774); Equilibrium disassociation constant (KD)..
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-PPP6C antibody [EPR8764]; Immunofluorescent analysis of HeLa cells labelling PPP6C with TA310774 at 1/100 dilution.

 

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