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Home Antibody All anti-PPP6C antibodies

Anti-PPP6C Antibody EPR8764

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310774
  • Rabbit Monoclonal antibody against PPP6C
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC426607) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)
IF(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human PPP6C was used as an immunogen.
Clone NameEPR8764 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IF Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 35 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens protein phosphatase 6, catalytic subunit (PPP6C), transcript variant 1
Alternative NamePP6; PP6C
Database LinkNP_001116827
Entrez Gene 5537 Human
Entrez Gene 67857 Mouse
Entrez Gene 171121 Rat
FunctionPPP6C is the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. The N-terminal domain of PPP6C restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. PPP6C also downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7 (1).
Related PathwayPhosphataseDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-PPP6C antibody [EPR8764]; All lanes : Anti-PPP6C antibody [EPR8764] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Fetal thymus lysate.Lane 3 : 293T cell lysate.Lane 4 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 35 kDa.
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Other-Anti-PPP6C antibody [EPR8764](TA310774); Equilibrium disassociation constant (KD)..
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Immunocytochemistry/ Immunofluorescence - Anti-PPP6C antibody [EPR8764]; Immunofluorescent analysis of HeLa cells labelling PPP6C with TA310774 at 1/100 dilution.
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