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Home Antibody All anti-PPP2CA antibodies

Anti-PPP2CA Antibody Y119

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300453
  • Rabbit Monoclonal Antibody against PPP2CA (Clone Y119)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419151) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for PPP2CA (NM_002715)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human PP2A was used as immunogen. This antibody detects both alpha and beta isoforms of PP2A.
Clone NameY119 IsotypeIgG
Species ReactivityHuman, Mouse, Rat ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:5,000-10,000; IHC: 1:250-500; ICC: 1:50; IP: 1: 100
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Protein A purified

Reference Data

Target NameHomo sapiens protein phosphatase 2, catalytic subunit, alpha isozyme (PPP2CA)
Alternative NamePP2Ac; PP2CA; PP2Calpha; RP-C
Database LinkNP_002706
FunctionProtein phosphatase type 2A (PP2A) is a protein serine/threonine phosphatase that controls fundamental cellular processes, including transcription, translation, metabolism, cell growth, apoptosis, and varied other signal transduction pathways (1-3). PP2A is comprised of a core enzyme, which is made up of catalytic C and regulatory A (PR65) subunits, and a secondary regulatory B subunit. This B subunit contains four different protein families. In response to EGF or insulin, it has been shown that Src phosphorylates PP2A at Tyr307, thereby inactivating PP2A (4).
Related Pathway
Cell cycle
TGF Beta Signaling Pathway
Wnt Signaling Pathway

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WB Image
Western blot - PP2A alpha and beta antibody [Y119]; Anti-PP2A alpha and beta antibody [Y119] at 1/10000 dilution + T47-D cell lysate.Predicted band size : 35 kDa.Observed band size : 36 kDa .
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - PP2A alpha and beta antibody [Y119]; TA300453,at a 1/250 dilution, staining human breast carcinoma by immunohistochemistry, Paraffin embedded tissue

 

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