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Home Antibody All anti-PPM1B antibodies

Anti-PPM1B TRUEMAB Antibody clone 3E8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA502900
  • PPM1B mouse monoclonal antibody,clone 3E8
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419156) , 20ug
100ul 325 In Stock
CF502900
  • Carrier-free (BSA/glycerol-free) PPM1B mouse monoclonal antibody,clone 3E8
100ug $450 3-4 weeks
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WB(1)
IHC(2)
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Also for PPM1B (NM_002706)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PPM1B(NP_002697) produced in HEK293 cell.
Clone Nameclone 3E8 IsotypeIgG2a
Species ReactivityHuman Concentration0.63 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB 1:2000, IHC 1:150,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens protein phosphatase, Mg2+/Mn2+ dependent, 1B (PPM1B), transcript variant 1
Alternative NamePP2C-beta-X; PP2CB; PP2CBETA; PPC2BETAX
Database LinkNP_002697
FunctionThe protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. [provided by RefSeq].
Related Pathway
MAPK signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PPM1B (RC212918, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PPM1B.
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PPM1B mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA502900)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PPM1B mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA502900)

 

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