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Home Antibody All anti-PPAPDC2 antibodies

Anti-PPAPDC2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306886
  • Rabbit Polyclonal PPAPDC2 Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403715) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IF(1)
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Also for PPAPDC2 (NM_203453)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenPPAPDC2 antibody was raised against a 13 amino acid peptide from near the carboxy terminus human PPAPDC2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 1 ug/ml, IF: 20 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens phosphatidic acid phosphatase type 2 domain containing 2 (PPAPDC2)
Alternative NamebA6J24.6; PDP1; PSDP
Database LinkNP_982278
Entrez Gene 403313 Human
Entrez Gene 74411 Mouse
Entrez Gene 619549 Rat
FunctionPPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity. PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation. PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid. PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts. It is widely expressed in human tissues. Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.
Related PathwayTransmembrane

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of PPAPDC2 in Raji cell lysate with PPAPDC2 antibody at 1 µg/ml in (A) the absence and (B) the presence of blocking peptide.
IF Image
Immunofluorescence of PPAPDC2 in Raji cells with PPAPDC2 antibody at 20 ug/mL.

 

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