Home Antibody All anti-POSTN antibodies
Also for POSTN (NM_006475)
|Peptide with sequence C-RKLQANKKVQGSRR, from the C Terminus of the protein sequence according to NP_006466.2; NP_001129406.1; NP_001129407.1; NP_001129408.1|
||WB: 1-3ug/ml, ELISA: 1:16,000
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide
|Homo sapiens periostin, osteoblast specific factor (POSTN), transcript variant 1|
|OSF-2; OSF2; PDLPOSTN; periostin; PN|
|Periostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.|
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Anti-POSTN (2ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.