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Home Antibody All anti-POSTN antibodies

Anti-POSTN Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA320204
  • Goat Polyclonal Periostin (POSTN) Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC427734) , 20ug
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence C-RKLQANKKVQGSRR, from the C Terminus of the protein sequence according to NP_006466.2; NP_001129406.1; NP_001129407.1; NP_001129408.1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml, ELISA: 1:16,000
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Reference Data

Target NameHomo sapiens periostin, osteoblast specific factor (POSTN), transcript variant 1
Alternative NameOSF-2; OSF2; PDLPOSTN; periostin; PN
Database LinkNP_006466
FunctionPeriostin is a disulfide linked 90 kDa, 811 amino acid protein originally isolated as a osteoblast-specific factor that functions as a cell adhesion molecule for preosteoblasts and is thought to be involved in osteoblast recruitment, attachment and spreading. Additionally, periostin expression has previously been shown to be significantly increased by both transforming growth factor beta 1(TGF beta 1) and bone morphogenetic protein (BMP2). Periostin mRNA is expressed in the developing mouse embryonic and fetal heart, and that it is localized to the endocardial cushions that ultimately divide the primitive heart tube into a four-chambered heart. Abnormal expression of periostin is also linked to angiogenesis and metastatsis in epithelial tumors.
Related Pathway

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WB Image
Anti-POSTN (2ug/ml) staining of MCF7 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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