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Home Antibody All anti-POR antibodies

Anti-POR TRUEMAB Antibody Clone OTI3H10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500572 anti-POR (Cytochrome P450 Reductase) mouse monoclonal antibody, clone OTI3H10 (formerly 3H10) 100ul $325 In Stock
LC424436 POR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500572 Carrier-free (BSA/glycerol-free) POR mouse monoclonal antibody, clone OTI3H10 (formerly 3H10) 100ug $450 3-4 weeks
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WB(1)
IHC(2)
IF(1)
FC(1)

OriGene Data

ImmunogenFull-length protein expressed in 293T cell transfected with human POR expression vector
Clone NameClone OTI3H10 IsotypeIgG1
Species ReactivityHuman Concentration0.8 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:1000, IHC 1:50, IF 1:100, Flow 1:100
Predicted MW Explanation 76.7 KDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens P450 (cytochrome) oxidoreductase (POR)
Alternative NameCPR; CYPOR; P450R
Database LinkNP_000932
Entrez Gene 5447 Human
FunctionThis gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome.
Related PathwayTransmembraneP450Druggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY POR (RC202172, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-POR.
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Immunohistochemical staining of paraffin-embedded pancreas tissue within the normal limits using anti-PORmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500572, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded endometrium tissue within the normal limits using anti-PORmouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500572, Dilution 1:50)
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Anti-POR mouse monoclonal antibody (TA500572) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY POR(RC202172).
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HEK293T cells transfected with either pCMV6-ENTRY POR(RC202172)(Red) or empty vector control plasmid(Blue) were immunostained with anti-POR mouse monoclonal(TA500572, Dilution 1:1,000), and then analyzed by flow cytometry.
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