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Anti-PNPLA2 Antibody EPR3444(2)
Also for PNPLA2 (NM_020376)
|A synthetic peptide corresponding to residues in human ATGL was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens patatin-like phospholipase domain containing 2 (PNPLA2)|
|1110001C14Rik; ATGL; FP17548; iPLA2zeta; PEDF-R; TTS-2.2; TTS2|
|Adipose triglyceride lipase (ATGL) catalyzes the initial step in triglyceride hydrolysis in adipocyte and non-adipocyte lipid droplets. It also has acylglycerol transacylase activity. ATGL may act coordinately with LIPE/HLS within the lipolytic cascade. It regulates adiposome size and may be involved in the degradation of adiposomes (1). Activity of ATGL is regulated by an activator protein annotated as α/β-fold domain-containing protein 5 (ABHD5), also known as CGI-58 (comparative gene identification 58) (2). Its highest expression is in adipose tissue (1).|
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Western blot - Adipose Triglyceride Lipase antibody [EPR3444(2)]; All lanes : Anti-Adipose Triglyceride Lipase antibody [EPR3444(2)] at 1/1000 dilution.Lane 1 : 3T3-L1 lysate.Lane 2 : A431 lysate.Lane 3 : A673 lysate.Lane 4 : Human heart tissue lysate.Lane 5 : Human skeletal muscle tissue lysate.Lane 6 : Human adipose tissue lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 55 kDa.Observed band size : 54 kDa .