Home Antibody All anti-PMVK antibodies
Anti-PMVK TRUEMAB Antibody clone 2F9
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PMVK (NM_006556)
|Full length human recombinant protein of human PMVK(NP_006547) produced in HEK293T cell.|
|WB, IF, FC
|| WB 1:2000, IF 1:100, FLOW 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens phosphomevalonate kinase (PMVK)|
|HUMPMKI; PMK; PMKA; PMKASE|
Entrez Gene 10654 Human
|This gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011]. |
|Druggable Genome Terpenoid backbone biosynthesisMetabolic pathways|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (RC202867, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK.
Anti-PMVK mouse monoclonal antibody (TA503449) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PMVK(RC202867).
HEK293T cells transfected with either RC202867 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PMVK antibody(TA503449), and then analyzed by flow cytometry.