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Home Antibody All anti-PMVK antibodies

Anti-PMVK TRUEMAB Antibody Clone OTI2F9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA503449 PMVK mouse monoclonal antibody, clone OTI2F9 (formerly 2F9) 100ul $325 In Stock
LC416571 PMVK HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503449 Carrier-free (BSA/glycerol-free) PMVK mouse monoclonal antibody, clone OTI2F9 (formerly 2F9) 100ug $450 3-4 weeks

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human PMVK(NP_006547) produced in HEK293T cell.
Clone NameClone OTI2F9 IsotypeIgG2a
Species ReactivityHuman Concentration0.32 mg/ml
Guaranteed Application *WB, IF, FC Suggested Dilutions WB 1:2000, IF 1:100, FLOW 1:100,
Predicted MW Explanation 21.8 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphomevalonate kinase (PMVK)
Alternative NameHUMPMKI; PMK; PMKA; PMKASE
Database LinkNP_006547
Entrez Gene 10654 Human
FunctionThis gene encodes a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of this protein is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. [provided by RefSeq, Sep 2011].
Related PathwayDruggable Genome Terpenoid backbone biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PMVK (RC202867, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PMVK.
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Anti-PMVK mouse monoclonal antibody (TA503449) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PMVK(RC202867).
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HEK293T cells transfected with either RC202867 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PMVK antibody(TA503449), and then analyzed by flow cytometry.
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