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Home Antibody All anti-PMAIP1 antibodies

Anti-PMAIP1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA318945
  • Rabbit polyclonal anti-Noxa antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402842) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for PMAIP1 (NM_021127)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 100 of human Noxa
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.2 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4ug/ml
Buffer100 µg (0.2mg/ml) protein A purified rabbit anti-Noxa polyclonal antibody in phosphate-buffered saline (PBS) containing 0.5% BSA, 30% glycerol, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)
Alternative NameAPR; NOXA
Database LinkNP_066950
FunctionNoxa is a BH3-only member of the Bcl-2 family. Expression of Noxa gene involves direct activation of its promotor by p53. Increased expression of Noxa protein occurs in normal thymocytes but not in p53-deficient thymocytes. Coimmunoprecipitation data suggest that Noxa protein may interact with proteins belonging to the Bcl-2 family, such as Bcl-xL and Mcl-1. Blocking the endogenous Noxa induction results in the suppression of apoptosis. These suggest Noxa may represent a candidate mediator of p53-induced apoptosis.
Related Pathway
Apoptosis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Noxa expression in Jurkat cell lysate.

 

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