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Anti-PLAGL1 Antibody EPR7523


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SKU Description Amount Price Availability*  
  • Rabbit Monoclonal antibody against PLAGL1
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human PLAGL1 was used as an immunogen.
Clone NameEPR7523 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, FC Suggested DilutionsWB: 1:10000 - 1:50000; FC: 1:10 - 1:100
BufferpH: 7.20; Preservative: 0.01% Sodium azide; Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens pleiomorphic adenoma gene-like 1 (PLAGL1), transcript variant 3
Alternative NameLOT1; ZAC; ZAC1
Database LinkNP_001074420
Entrez Gene 5325 Human
FunctionPLAGL1 is a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, its overexpression during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). PLAGL1 is imprinted, with preferential expression of the paternal allele in many tissues; however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-PLAGL1 / ZAC antibody [EPR7523]; All lanes : Anti-PLAGL1 / ZAC antibody [EPR7523] at 1/10000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human fetal kidney lysate.Lane 3 : 293T cell lysate.Lane 4 : HepG2 cell lysate.Lane 5 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 51 kDa.Observed band size : 51 kDa.
Other-Anti-PLAGL1 / ZAC antibody [EPR7523](TA310761); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-PLAGL1 / ZAC antibody [EPR7523]; TA310761 at 1/10 dilution staining PLAGL1 / ZAC in permeabilized HepG2 cells by Flow Cytometry (red) or a rabbit IgG negative (green).


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