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Anti-PIK3R5 TRUEMAB Antibody Clone OTI2C6
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for PIK3R5 (NM_014308)
|Full length human recombinant protein of human PIK3R5(NP_055123) produced in HEK293T cell.|
|Human , Dog , Rat , Monkey , Mouse
|WB, IHC, IF
||WB 1:200~2000, IHC 1:150, IF 1:100,
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), transcript variant 2|
|F730038I15Rik; FOAP-2; p101; P101-PI3K|
Entrez Gene 23533 Human
Entrez Gene 320207 Mouse
Entrez Gene 497931 Rat
Entrez Gene 722027 Monkey
Entrez Gene 612805 Dog
|Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011].|
|Druggable Genome ErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisVEGF signaling pathwayMore Pathways >> |
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3R5 (RC222249, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3R5.
Western blot analysis of extracts (10ug) from 8 Human tissue by using anti-PIK3R5 monoclonal antibody at 1:200 (1: Testis; 2: Uterus; 3: Breast; 4: Brain; 5: Liver; 6: Ovary; 7: Thyroid gland; 8: Colon).
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PIK3R5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505893)
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PIK3R5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505893)
Immunohistochemical staining of paraffin-embedded Human tonsil within the normal limits using anti-PIK3R5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505893)
Anti-PIK3R5 mouse monoclonal antibody (TA505893) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PIK3R5(RC222249).