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Home Antibody All anti-PIK3R5 antibodies

Anti-PIK3R5 TRUEMAB Antibody Clone OTI2A6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA505816
  • PIK3R5 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402310) , 20ug Explanation
100ul $325 In Stock
CF505816
  • Carrier-free (BSA/glycerol-free) PIK3R5 mouse monoclonal antibody, clone OTI2A6 (formerly 2A6)
100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)
IHC(3)
IF(1)

OriGene Data

ImmunogenFull length human recombinant protein of human PIK3R5(NP_055123) produced in HEK293T cell.
Clone NameClone OTI2A6 IsotypeIgG2b
Species ReactivityHuman , Dog , Rat , Monkey , Mouse Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:200~2000, IHC 1:150, IF 1:100,
Predicted MW Explanation 97.2 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphoinositide-3-kinase, regulatory subunit 5 (PIK3R5), transcript variant 2
Alternative NameF730038I15Rik; FOAP-2; p101; P101-PI3K
Database LinkNP_055123
Entrez Gene 23533 Human
Entrez Gene 320207 Mouse
Entrez Gene 497931 Rat
Entrez Gene 722027 Monkey
Entrez Gene 612805 Dog
FunctionPhosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011].
Related PathwayDruggable Genome ErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisVEGF signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3R5 (RC222249, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3R5.
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Western blot analysis of extracts (35ug) from 9 different cell lines by usin g anti-PIK3R5 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
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Immunohistochemical staining of paraffin-embedded Human colon tissue within the normal limits using anti-PIK3R5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505816)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PIK3R5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505816)
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-PIK3R5 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA505816)
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Anti-PIK3R5 mouse monoclonal antibody (TA505816) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PIK3R5(RC222249).
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