Anti-PIK3C2A Antibody, Clone 2D9

Also for PIK3C2A (NM_002645)

OriGene Data

Immunogen	Human recombinant protein fragment corresponding to amino acids 230-560 of human PIK3C2A (NP_002636) produced in E.coli.
Clone Name	Clone 2D9	Isotype	IgG2a
Species Reactivity	Human	Concentration	0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *	WB, IHC	Suggested Dilutions	WB 1:2000, IHC 1:150,
Buffer	PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification	Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)

Reference Data

Target Name	Homo sapiens phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha (PIK3C2A)
Alternative Name	CPK; PI3-K-C2(ALPHA); PI3-K-C2A
Database Link	NP_002636
Function	The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling. [provided by RefSeq, Jul 2008].
Related Pathway

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WB Image

E.coli lysate (left lane) and E.coli lysate expressing human recombinant protein fragment corresponding to amino acids 230-560 of human PIK3C2A (NP_002636) were separated by SDS-PAGE and immunoblotted with anti-PIK3C2A.

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Human liver tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human liver tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

IHC Image

Immunohistochemical staining of paraffin-embedded Human tonsil using anti-PIK3C2A mouse monoclonal antibody. (TA801728)

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Anti-PIK3C2A TrueMAB Antibody Clone 2D9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

OriGene Data

Reference Data