Home Antibody All anti-PIK3AP1 antibodies
Anti-PIK3AP1 TRUEMAB Antibody clone 7B12
TrueMAB Antibodies - Made against Authentic Protein Antigens
Also for PIK3AP1 (NM_152309)
|Full length human recombinant protein of human PIK3AP1 (NP_689552) produced in HEK293T cell.|
|WB, IHC, IF, FC
||WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100
|PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1)|
Entrez Gene 118788 Human
|Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B cells via activation of REL (By similarity).|
|Druggable Genome B cell receptor signaling pathway|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3AP1 (RC214125, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3AP1.
Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-PIK3AP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501760, Dilution 1:50)
Anti-PIK3AP1 mouse monoclonal antibody (TA501760) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PIK3AP1(RC214125).
HEK293T cells transfected with either RC214125 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PIK3AP1 antibody(TA501760), and then analyzed by flow cytometry.