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Home Antibody All anti-PIAS2 antibodies

Anti-PIAS2 Antibody EPR2582(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310758
  • Rabbit Monoclonal antibody against PIAS2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401487) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
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Also for PIAS2 (NM_004671)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PIAS2 was used as an immunogen.
Clone NameEPR2582(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; ICC/IF: 1:250 - 1:500
Predicted MW Explanation 68 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,IHC-P or IP.

Reference Data

Target NameHomo sapiens protein inhibitor of activated STAT, 2 (PIAS2), transcript variant beta
Alternative NameARIP3; DIP; MIZ; MIZ1; PIASX; PIASX-ALPHA; PIASX-BETA; SIZ2; ZMIZ4
Database LinkNP_004662
Entrez Gene 9063 Human
Entrez Gene 17344 Mouse
Entrez Gene 83422 Rat
FunctionPIAS2 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. It plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway (1).
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell - PluripotencyTranscription Factors Ubiquitin mediated proteolysisJak-STAT signaling pathwayPathways in cancerSmall cell lung cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PIAS2 antibody [EPR2582(2)]; All lanes : Anti-PIAS2 antibody [EPR2582(2)] at 1/1000 dilution.Lane 1 : HepG2 cell lysate.Lane 2 : Human fetal kidney tissue lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 68 kDa.

 

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