Home Antibody All anti-PHOX2A antibodies
Anti-PHOX2A Antibody EPR9070
Also for PHOX2A (NM_005169)
|A synthetic peptide corresponding to residues in human PHOX2A was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|Preservative: 0.01% Sodium azide|
Constituents: 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
|Homo sapiens paired-like homeobox 2a (PHOX2A)|
|ARIX; CFEOM2; FEOM2; NCAM2; PMX2A|
|PHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless protein. It plays a central role in development of the autonomic nervous system. PHOX2A regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor. Mutations in PHOX2A have been associated with autosomal recessive congenital fibrosis of the extraocular muscles (1).|
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Western blot - Anti-PHOX2A antibody [EPR9070]; All lanes : Anti-PHOX2A antibody [EPR9070] at 1/1000 dilution.Lane 1 : U-87 MG cell lysate.Lane 2 : Neuro-2a cell lysate.Lane 3 : SH-SY5Y cell lysate.Lane 4 : HeLa cell lysate.Lane 5 : C6 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.developed using the ECL technique.Predicted band size : 30 kDa.