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Home Antibody All anti-PHOX2A antibodies

Anti-PHOX2A Antibody EPR9070

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310757
  • Rabbit Monoclonal antibody against PHOX2A
100ul 325 3-7 Days
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WB(1)
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Also for PHOX2A (NM_005169)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PHOX2A was used as an immunogen.
Clone NameEPR9070 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
BufferPreservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens paired-like homeobox 2a (PHOX2A)
Alternative NameARIX; CFEOM2; FEOM2; NCAM2; PMX2A
Database LinkNP_005160
Entrez Gene 401 Human
Entrez Gene 11859 Mouse
Entrez Gene 116648 Rat
FunctionPHOX2A contains a paired-like homeodomain most similar to that of the Drosophila aristaless protein. It plays a central role in development of the autonomic nervous system. PHOX2A regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. PHOX2A has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor. Mutations in PHOX2A have been associated with autosomal recessive congenital fibrosis of the extraocular muscles (1).
Related PathwayTranscription Factors

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PHOX2A antibody [EPR9070]; All lanes : Anti-PHOX2A antibody [EPR9070] at 1/1000 dilution.Lane 1 : U-87 MG cell lysate.Lane 2 : Neuro-2a cell lysate.Lane 3 : SH-SY5Y cell lysate.Lane 4 : HeLa cell lysate.Lane 5 : C6 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.developed using the ECL technique.Predicted band size : 30 kDa.

 

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