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Home Antibody All anti-PHKG2 antibodies

Anti-PHKG2 TRUEMAB Antibody Clone OTI2E5

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA800343 PHKG2 mouse monoclonal antibody, clone OTI2E5 (formerly 2E5) 100ul $325 In Stock
LC400111 PHKG2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF800343 Carrier-free (BSA/glycerol-free) PHKG2 mouse monoclonal antibody, clone OTI2E5 (formerly 2E5) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(3)

OriGene Data

ImmunogenHuman recombinant protein fragment corresponding to amino acids 1-216 of human PHKG2 (NP_000285) produced in E.coli.
Clone NameClone OTI2E5 IsotypeIgG2a
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC Suggested Dilutions WB 1:500,
Predicted MW Explanation 46.3 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphorylase kinase, gamma 2 (testis) (PHKG2), transcript variant 1
Alternative NameGSD9C
Database LinkNP_000285
Entrez Gene 5261 Human
FunctionPhosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Related PathwayProtein KinaseDruggable Genome Calcium signaling pathwayInsulin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PHKG2 (RC200597, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PHKG2.
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PHKG2 mouse monoclonal antibody. (TA800343) Dilution: 1:150
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PHKG2 mouse monoclonal antibody. (TA800343) Dilution: 1:150
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Immunohistochemical staining of paraffin-embedded Human endometrium tissue within the normal limits using anti-PHKG2 mouse monoclonal antibody. (TA800343) Dilution: 1:150
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