Home Antibody All anti-PHKA1 antibodies
Also for PHKA1 (NM_001122670)
|Recombinant fragment corresponding to a region within amino acids 828 and 1062 of PHKA1 (Uniprot ID#P46020)|
|Human (Predicted: Mouse, Rat)
|WB, IHC, IF
||ICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (96%), Rat (95%)
|Homo sapiens phosphorylase kinase, alpha 1 (muscle) (PHKA1), transcript variant 2|
Entrez Gene 5255 Human
Entrez Gene 18679 Mouse
Entrez Gene 64561 Rat
|The PHKA1 gene encodes the alpha subunit of muscle phosphorylase kinase (EC 22.214.171.124), a key regulatory enzyme of glycogen metabolism. Phosphorylase kinase consists of 4 copies of an alpha-beta-gamma-delta tetramer. The alpha, beta (PHKB; MIM 172490), and gamma (PHKG1; MIM 172470 and PHKG2; MIM 172471) subunits have several isoforms; the delta subunit is calmodulin (CALM1; MIM 114180). PHKA2 (MIM 306000) encodes the alpha subunit of liver-specific phosphorylase kinase and is also located on the X chromosome.[supplied by OMIM]|
|Druggable Genome Calcium signaling pathwayInsulin signaling pathway|
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Sample (30 ug of whole cell lysate). A: HeLa. 7.5% SDS PAGE. TA308404 diluted at 1:1000
Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using PHKA1(TA308404) antibody at 1:500 dilution.
Immunofluorescence analysis of methanol-fixed HeLa, using PHKA1(TA308404) antibody at 1:200 dilution.