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Home Antibody All anti-PGR antibodies

Anti-PGR PHOSPHO Antibody 608

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309221
  • mouse Anti-Progesterone Receptor (Ser294) Antibody (Phospho-Specific)
100ul 325 3-7 Days
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WB(1)
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Also for PGR (NM_000926)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser294 conjugated to KLH
Clone Name608 IsotypeIgG1
Species Reactivityhuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000, IHC: 1:1000
Buffer100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification Protein G purified

Reference Data

Target NameHomo sapiens progesterone receptor (PGR), transcript variant 2
Alternative NameNR3C3; PR
Database LinkNP_000917
FunctionThis gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. [provided by RefSeq].
Related Pathway

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WB Image
Western blot of whole cell T47D lysate prepared from cells that had been incubated in the presence of the synthetic progestin agonist R5020 (500 nM) showing specific immunolabeling of the ~90k PR-A isoform and the ~120 PR-B isoform of the progesterone receptor phosphorylated at Ser294. The immunolabeling is blocked by the phosphopeptide used as the antigen (not shown).

 

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