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Anti-PGR Antibody YR85
|A synthetic peptide corresponding to residues near N-terminus of human Progesterone Receptor was used as immunogen. The antibody does not cross-react with other NR3 family members.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250; ICC: 1:50; IP: 1:150; ICC/IF: Use a concentration of 5 ug/ml
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt.
|Homo sapiens progesterone receptor (PGR), transcript variant 2|
Entrez Gene 5241 Human
|This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform A only, and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform B has not been clearly determined. [provided by RefSeq]. |
|Nuclear Hormone ReceptorTranscription FactorsDruggable Genome Oocyte meiosisProgesterone-mediated oocyte maturation|
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Western blot - Progesterone Receptor antibody [YR85]; Anti-Progesterone Receptor antibody [YR85] at 1/10000 dilution + T47D cell lysate.Predicted band size : 99 kDa.Observed band size : 99,135 kDa.
Other-Anti-Progesterone Receptor antibody [YR85](TA303633); Equilibrium disassociation constant (KD).
Immunohistochemistry (Paraffin-embedded sections) - Progesterone Receptor antibody [YR85]; Immunohistochemical analysis of progesterone receptor expression in paraffin embedded human breast carcinoma, using 1/100 TA303633.