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Home Antibody All anti-PDGFRB antibodies

Anti-PDGFRB TRUEMAB Antibody Clone OTI1E8

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA506230 PDGFRB mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 100ul $325 In Stock
LC400921 PDGFRB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF506230 Carrier-free (BSA/glycerol-free) PDGFRB mouse monoclonal antibody, clone OTI1E8 (formerly 1E8) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(1)
IHC(7)
IF(1)
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Also for PDGFRB (NM_002609)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PDGFRB(NP_002600) produced in HEK293T cell.
Clone NameClone OTI1E8 IsotypeIgG1
Species ReactivityHuman Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF Suggested Dilutions WB 1:4000, IHC 1:150, IF 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB)
Alternative NameCD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1
Database LinkNP_002600
Entrez Gene 5159 Human
FunctionThis gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008].
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome MAPK signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionFocal adhesionGap junctionRegulation of actin cytoskeletonMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDGFRB (RC206377, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDGFRB.
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-PDGFRB mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120C for 3min, TA506230)
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Anti-PDGFRB mouse monoclonal antibody (TA506230) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDGFRB(RC206377).
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