Home Antibody All anti-PDE3B antibodies
Also for PDE3B (NM_000922)
|Synthetic peptide surrounding amino acid 948 of mouse PDE3B. |
|Human, mouse, rat
||WB: 0.5-4 ug/ml
|100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.|
|Homo sapiens phosphodiesterase 3B, cGMP-inhibited (PDE3B)|
|The phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B. Phosphodiesterases (PDE) are crucial in the regulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. PDE3B has two splice variants that are expressed in adipocyte tissue, hepatocyte, kidney, spermatocytes and embryonic neuroepithelium. Both PDE3A and PDE3B are potential targets for the treatment of obesity. |
Signaling by GPCR
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Western blot analysis of PDE3B with lysate from 3T3 cells.