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Home Antibody All anti-PDE3B antibodies

Anti-PDE3B Antibody


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SKU Description Amount Price Availability*  
  • Rabbit polyclonal anti-PDE3B antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424435) , 20ug Explanation
200ug $325 3-7 Days
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Also for PDE3B (NM_000922)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSynthetic peptide surrounding amino acid 948 of mouse PDE3B.
Clone Name IsotypeRabbit IgG
Species ReactivityHuman, mouse, rat Concentration0.5mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-4 ug/ml
Buffer100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Purification Affinity purified

Reference Data

Target NameHomo sapiens phosphodiesterase 3B, cGMP-inhibited (PDE3B)
Alternative NamecGIPDE1; HcGIP1
Database LinkNP_000913
Entrez Gene 5140 Human
Entrez Gene 18576 Mouse
Entrez Gene 29516 Rat
FunctionThe phosphodiesterase type-3 (PDE3) family is comprised of 2 isoforms, PDE3A and PDE3B. Phosphodiesterases (PDE) are crucial in the regulation of the intracellular level of the second messenger cAMP by hydrolyzing cAMP to 5’AMP. PDE3B has two splice variants that are expressed in adipocyte tissue, hepatocyte, kidney, spermatocytes and embryonic neuroepithelium. Both PDE3A and PDE3B are potential targets for the treatment of obesity.
Related PathwayTransmembraneDruggable Genome Purine metabolismInsulin signaling pathwayProgesterone-mediated oocyte maturation

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of PDE3B with lysate from 3T3 cells.


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