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Home Antibody All anti-PDE1B antibodies

Anti-PDE1B TRUEMAB Antibody Clone 6E4

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA503319
  • PDE1B mouse monoclonal antibody,clone 6E4
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400337) , 20ug
100ul 325 In Stock
CF503319
  • Carrier-free (BSA/glycerol-free) PDE1B mouse monoclonal antibody,clone 6E4
100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(1)
FC(2)
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Also for PDE1B (NM_000924)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PDE1B(NP_000915) produced in HEK293T cell.
Clone NameClone 6E4 IsotypeIgG2b
Species ReactivityHuman Concentration1.00 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens phosphodiesterase 1B, calmodulin-dependent (PDE1B), transcript variant 1
Alternative NamePDE1B1; PDES1B
Database LinkNP_000915
FunctionCyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1B, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).[supplied by OMIM].
Related Pathway
Signaling by GPCR

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PDE1B (RC206588, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PDE1B.
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PDE1B mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0, TA503319)
IF Image
Anti-PDE1B mouse monoclonal antibody (TA503319) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PDE1B(RC206588).
FC Image
HEK293T cells transfected with either RC206588 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PDE1B antibody(TA503319), and then analyzed by flow cytometry.
FC Image
Flow cytometric Analysis of Jurkat cells, using anti-PDE1B antibody(TA503319),(Red), compared to a nonspecific negative control antibody,(Blue).

 

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