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Home Antibody All anti-PCSK9 antibodies

Anti-PCSK9 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303007
  • Goat Polyclonal Antibody against PCSK9
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403563) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for PCSK9 (NM_174936)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence CRSRHLAQASQELQ, from the C Terminus of the protein sequence according to NP_777596.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 0.2ug/ml. IHC: 2-6ug/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens proprotein convertase subtilisin/kexin type 9 (PCSK9), transcript variant 1
Alternative NameFH3; HCHOLA3; LDLCQ1; NARC-1; NARC1; PC9
Database LinkNP_777596
FunctionThis gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3). [provided by RefSeq].
Related Pathway

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WB Image
TA303007 staining (0.2µg/ml) of McA cell lysates: untransfected (1), transfected with wild type human pcsk9 (2), transfected with S127R human pcsk9 (3). Data kindly provided by Dr. X-M Sun, Hammersmith Hospital, London.

 

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