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Home Antibody All anti-PCK1 antibodies

Anti-PCK1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305772
  • Goat Anti-PCK1 / PEPCKC (internal) Antibody
100ug 325 3-7 Days
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IHC(1)
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Also for PCK1 (NM_002591)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-HVNWFRKDKEGK, from the internal region of the protein sequence according to NP_002582.3.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *IHC Suggested DilutionsIHC: 2-4ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens phosphoenolpyruvate carboxykinase 1 (soluble) (PCK1)
Alternative NamePEPCK-C; PEPCK1; PEPCKC
Database LinkNP_002582
Entrez Gene 5105 Human
Entrez Gene 18534 Mouse
Entrez Gene 362282 Rat
Entrez Gene 403560 Dog
FunctionThis gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. [provided by RefSeq].
Related PathwayDruggable Genome Glycolysis / GluconeogenesisCitrate cycle (TCA cycle)Pyruvate metabolismMetabolic pathwaysPPAR signaling pathwayInsulin signaling pathwayMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

IHC Image
TA305772 (2ug/ml) staining of paraffin embedded Human Cerebral Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

 

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