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Home Antibody All anti-PCDH12 antibodies

Anti-PCDH12 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306741
  • Rabbit Polyclonal PCDH12 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC413902) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for PCDH12 (NM_016580)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPCDH12 antibody was raised against a 17 amino acid peptide near the amino terminus of human PCDH12.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens protocadherin 12 (PCDH12)
Alternative NameVE-cadherin-2; VECAD2
Database LinkNP_057664
FunctionProtocadherins comprise the largest group within the cadherin family of calcium-dependent cell-cell adhesion molecules. Protocadherin 12 (PCDH12) was initially identified through PCR screening of mouse heart microvascular endothelial cell RNA; further experiments revealed its mRNA to be strongly expressed in highly vascularized organs such as lung and kidney, in addition to glycogen-rich trophoblasts in the placenta. PCDH12-null mice are viable and fertile, but show reduced placental and embryonic sizes when compared to wild-type mice. Further studies showed significant expression changes in 2,289 genes, including those involved in tissue morphogenesis, angiogenesis, cell-matrix adhesion and migration, immune response and chromatin remodeling. This antibody is predicted to not cross-react with PCDH18.
Related Pathway

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WB Image
Western blot analysis of PCDH12 in K562 cell lysate with PCDH12 antibody at 2 ug/ml.
IHC Image
Immunohistochemistry of PCDH12 in rat lung tissue with PCDH12 antibody at 5 ug/ml.

 

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