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Home Antibody All anti-PBX1 antibodies

Anti-PBX1 TRUEMAB Antibody Clone OTI1C11

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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SKU Description Amount Price Availability*  
TA503065 PBX1 mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) 100ul $379 In Stock
LC400918 PBX1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF503065 Carrier-free (BSA/glycerol-free) PBX1 mouse monoclonal antibody, clone OTI1C11 (formerly 1C11) 100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(1)
FC(1)

OriGene Data

ImmunogenFull length human recombinant protein of human PBX1(NP_002576) produced in HEK293 cell.
Clone NameClone OTI1C11 IsotypeIgG1
Species ReactivityHuman Concentration0.29 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
Predicted MW Explanation 46.4 kDa
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens pre-B-cell leukemia homeobox 1 (PBX1), transcript variant 1
Alternative NameDKFZp686B09108; MGC126627
Database LinkNP_002576
Entrez Gene 5087 Human
FunctionThis gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1;19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PBX1 (RC210944, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PBX1.
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-PBX1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA503065)
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Anti-PBX1 mouse monoclonal antibody (TA503065) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PBX1(RC210944).
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HEK293T cells transfected with either RC210944 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PBX1 antibody(TA503065), and then analyzed by flow cytometry.
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