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Home Antibody All anti-PAX8 antibodies

Anti-PAX8 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308698
  • Rabbit polyclonal antibody to PAX8CC (paired box 8)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC429402) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IP(1)
IHC(1)
IF(1)
Assay(1)
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Also for PAX8 (NM_013992)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 204 of PAX8
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, ASSAY, IHC, IF, IP Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 43kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens paired box 8 (PAX8), transcript variant PAX8E
Alternative NameOTTHUMP00000158659; OTTHUMP00000158660; paired domain gene 8; paired box 8
Database LinkNP_054698
Entrez Gene 7849 Human
FunctionThis gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternateively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq]
Related PathwayTranscription FactorsDruggable Genome Pathways in cancerThyroid cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug whole cell lysate). A:293T. 10% SDS PAGE. TA308698 diluted at 1:1000
Assay Image
PAX8 antibody immunoprecipitates PAX8 protein-DNA in ChIP experiments. ChIP Sample: 293T whole cell lysate/extract A. 5 ug preimmune rabbit IgG B. 5 ug of PAX8 antibody (TA308698) The precipitated DNA was detected by PCR with primer set targeting to E2F1
IHC Image
PAX8 antibody detects PAX8 protein at nucleus on BT483 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded BT483 xenograft. PAX8 antibody (TA308698) dilution: 1:500.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A549, using PAX8(TA308698) antibody at 1:200 dilution.
IP Image
PAX8 antibody immunoprecipitates PAX8 protein in IP experiments. IP Sample: 1000 ug 293T whole cell lysate/extract A. 40 ug 293T whole cell lysate/extract B. Control with 2 ug of preimmune rabbit IgG C. Immunoprecipitation of PAX8 protein by 2 ug of PAX8

 

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