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Anti-PAX6 Antibody EPR3352(2)
Also for PAX6 (NM_001604)
|A synthetic peptide corresponding to residues in the C-terminus of human PAX6 was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; FC: 1:100 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for ICC,IHC-P or IP.
|Homo sapiens paired box 6 (PAX6), transcript variant 2|
|AN; AN2; D11S812E; MGDA; WAGR|
|PAX6 is one of many human homologs of the Drosophila melanogaster gene prd (1). It is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas (2). PAX6 is required for the differentiation of pancreatic islet alpha cells, and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. It regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (2). Mutations in this protein are known to cause ocular disorders such as aniridia and Peter's anomaly (1).|
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Western blot - PAX6 antibody [EPR3352(2)]; All lanes : Anti-PAX6 antibody [EPR3352(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.