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Home Antibody All anti-PAX6 antibodies

Anti-PAX6 Antibody EPR3352(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307535
  • Rabbit monoclonal antibody against PAX6(clone EPR3352(2))
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419854) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for PAX6 (NM_001604)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the C-terminus of human PAX6 was used as an immunogen.
Clone NameEPR3352(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; FC: 1:100 - 1:500
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens paired box 6 (PAX6), transcript variant 2
Alternative NameAN; AN2; D11S812E; MGDA; WAGR
Database LinkNP_001595
FunctionPAX6 is one of many human homologs of the Drosophila melanogaster gene prd (1). It is a transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas (2). PAX6 is required for the differentiation of pancreatic islet alpha cells, and competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. It regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (2). Mutations in this protein are known to cause ocular disorders such as aniridia and Peter's anomaly (1).
Related Pathway

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WB Image
Western blot - PAX6 antibody [EPR3352(2)]; All lanes : Anti-PAX6 antibody [EPR3352(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : K562 cell lysate.Lane 3 : HepG2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 47 kDa.Observed band size : 47 kDa.

 

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