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Home Antibody All anti-PARP1 antibodies

Anti-PARP1 Antibody E102

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Specifications Citations (1) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303384
  • Rabbit monoclonal antibody against PARP-1 ( p116/25)(E102)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400609) , 20ug
100ul $325 In Stock
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Also for PARP1 (NM_001618)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to N-terminal residues of human PARP-1 was used as immunogen. The antibody should recognize both pro-form and p25 cleaved-form of PARP-1.
Clone NameE102 IsotypeRabbit IgG
Species ReactivityHuman, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application * Suggested DilutionsWB: 1:500 - 1,000; IHC: 1:25; ICC: 1:100; FC: 1:50
Buffer50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.

Reference Data

Target NameHomo sapiens poly (ADP-ribose) polymerase 1 (PARP1)
Alternative NameADPRT; ADPRT 1; ADPRT1; ARTD1; pADPRT-1; PARP; PARP-1; PPOL
Database LinkNP_001609
FunctionThis gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq].
Related Pathway

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