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Home Antibody All anti-PARK2 antibodies

Anti-PARK2 PHOSPHO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309209
  • Rabbit Anti-Parkin (Ser101) Antibody (Phospho-Specific)
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic phospho-peptide corresponding to amino acid residues surrounding Ser101 conjugated to KLH
Clone Name IsotypeIgG
Species Reactivityhuman ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
Buffer100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Purification Affinity Purified

Reference Data

Target NameHomo sapiens parkin RBR E3 ubiquitin protein ligase (PARK2), transcript variant 1
Alternative NameAR-JP; LPRS2; PDJ; PRKN
Database LinkNP_004553
FunctionThe precise function of this gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of this gene produces multiple transcript variants encoding distinct isoforms. Additional splice variants of this gene have been described but currently lack transcript support. [provided by RefSeq].
Related Pathway

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WB Image
Western blot of HEK293 cells transfected with Parkin WT (Phospho) and Parkin S101 mutant (non-phospho) showing the phospho-specific immunolabeling of the ~ 52 k parkin protein. The immunolabeling is absent in the parkin S101 mutant.

 

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