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Anti-PAPPA2 Antibody Polyclonal
Also for PAPPA2 (NM_020318)
|PLAC3 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human PLAC3.|
|Human, Mouse, Rat
||ELISA, WB: 1 ug/ml, ICC: 10 ug/ml, IF: 20 ug/ml
|PLAC3 Antibody is supplied in PBS containing 0.02% sodium azide.|
|PLAC3 Antibody is affinity chromatography purified via peptide column. (Protein A or G Sepharose)
|Homo sapiens pappalysin 2 (PAPPA2), transcript variant 1|
|PAPP-A2; PAPP-E; PAPPE; PLAC3|
|PLAC3 Antibody: PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.|
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Western blot analysis of PLAC3 in HeLa cell lysate with PLAC3 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry of PLAC3 in HeLa cells with PLAC3 antibody at 10 ug/mL.