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Home Antibody All anti-PANK2 antibodies

Anti-PANK2 TRUEMAB Antibody Clone OTI3H9

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (2) Related Products Product Documents
SKU Description Amount Price Availability*  
TA501321 anti-PANK2 mouse monoclonal antibody, clone OTI3H9 (formerly 3H9) 100ul $379 In Stock
LC406998 PANK2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF501321 Carrier-free (BSA/glycerol-free) PANK2 mouse monoclonal antibody, clone OTI3H9 (formerly 3H9) 100ug $450 3 Days
Conjugation is available for this antibody: choose conjugation type
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WB(3)
IHC(3)
IF(1)
FC(2)
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Also for PANK2 (NM_153638)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenFull length human recombinant protein of human PANK2(NP_705902) produced in HEK293T cell.
Clone NameClone OTI3H9 IsotypeIgG2a
Species ReactivityHuman, Dog, Rat, Monkey Concentration1 mg/ml
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:1000~2000, IHC 1:50, IF 1:100, FLOW 1:100
Predicted MW Explanation 59.1 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens pantothenate kinase 2 (PANK2), transcript variant 1
Alternative NameC20orf48; HARP; HSS; NBIA1; PKAN
Database LinkNP_705902
Entrez Gene 80025 Human
Entrez Gene 296167 Rat
Entrez Gene 717639 Monkey
Entrez Gene 477168 Dog
FunctionThis gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal biosynthetic pathway leading to CoA and is itself subject to regulation through feedback inhibition by acyl CoA species. Mutations in this gene are associated with HARP syndrome and pantothenate kinase-associated neurodegeneration (PKAN), formerly Hallervorden-Spatz syndrome. Alternative splicing, involving the use of alternate first exons, results in multiple transcripts encoding different isoforms. [provided by RefSeq].
Related PathwayDruggable Genome Pantothenate and CoA biosynthesisMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PANK2 (RC215676, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PANK2.
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Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-PANK2 monoclonal antibody.
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Figure from citation: Western Blot of PANK2 protein level by using anti-PANK2 antibody in different mitochondrial compartments isolated from WT mouse brain and WT mouse fibroblasts. Dilution: 1:2000 View Citation
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Immunohistochemical staining of paraffin-embedded Human liver tissue within the normal limits using anti-PANK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501321, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Human prostate tissue within the normal limits using anti-PANK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501321, Dilution 1:50)
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Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-PANK2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA501321, Dilution 1:50)
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Anti-PANK2 mouse monoclonal antibody (TA501321) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PANK2(RC215676).
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HEK293T cells transfected with either RC215676 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-PANK2 antibody(TA501321), and then analyzed by flow cytometry.
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Flow cytometric Analysis of Jurkat cells, using anti-PANK2 antibody(TA501321),(Red), compared to a nonspecific negative control antibody(TA50011),(Blue).
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