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Home Antibody All anti-PAK4 antibodies

Anti-PAK4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300645
  • Rabbit Polyclonal Antibody against PAK4
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417002) , 20ug
100ul 379 3-7 Days
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WB(1)
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Also for PAK4 (NM_005884)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-terminus of human PAK4 was used as immunogen.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
BufferPreservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Protein A purified
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens p21 protein (Cdc42/Rac)-activated kinase 4 (PAK4), transcript variant 1
Alternative Namep21(CDKN1A)-activated kinase 4; p21-activated kinase 4; protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs; p21 protein (Cdc42/Rac)-activated kinase 4
Database LinkNP_005875
Functionp21-activated kinase 4 (PAK4) is a member of a family of serine/threonine protein kinase defined by their interaction with the small GTPases, Cdc42 and Rac (1-2). The PAK proteins can be essentially divided into two categories, groups I (PAK1, PAK2 and PAK3) and group II (PAK4, PAK5 and PAK6), based on their structures (3). PAK4 has been shown to regulate cytoskeletal organization and to protect cells from apoptosis induced by multiple stimuli, including serum withdrawal, tumor necrosis factor- (TNF) treatment, or UV irradiation (4). PAK4 expression is elevated in many cancer cell lines, and activated PAK4 is highly transforming, suggesting an important role in tumorigenesis (5).
Related Pathway
Focal Adhesion

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WB Image
Western blot - Anti-PAK4 antibody; Anti-PAK4 antibody at 1/1000 dilution + SH-SY-5Y cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 64 kDa.Observed band size : 68 kDa .

 

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