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Anti-PAK3 Antibody EP797Y


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SKU Description Amount Price Availability*  
TA303629 Rabbit monoclonal antibody against PAK3 (N-term)(EP797Y) 100ul $325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-terminus of human PAK3 was used as immunogen.
Clone NameEP797Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:10,000-50,000; IHC: 1:100-250; ICC: 1: 100-250; IP: 1:50
Predicted MW Explanation 62 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens p21 protein (Cdc42/Rac)-activated kinase 3 (PAK3), transcript variant 2
Alternative NamebPAK; CDKN1A; hPAK3; MRX30; MRX47; OPHN3; PAK3beta
Database LinkNP_002569
Entrez Gene 5063 Human
Entrez Gene 18481 Mouse
Entrez Gene 29433 Rat
FunctionPAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Related PathwayProtein KinaseStem cell - PluripotencyDruggable Genome ErbB signaling pathwayAxon guidanceFocal adhesionT cell receptor signaling pathwayRegulation of actin cytoskeletonRenal cell carcinomaMore Pathways >>

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - PAK3 antibody [EP797Y]; Anti-PAK3 antibody [EP797Y] at 1/50000 dilution + fetal brain lysate at 10 ug.Predicted band size : 62 kDa.Observed band size : 65 kDa .

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PAK3 antibody [EP797Y]; TA303629 at a 1:100 dilution staining PAK3 in human brain glioma.


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