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Anti-PAK2 PHOSPHO Antibody EPR658(2)
Also for PAK2 (NM_002577)
|A phospho-specific peptide corresponding to residues surrounding Serine 20 of human PAK2 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:20000; ICC/IF: 1:100 - 1:250
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05% (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens p21 protein (Cdc42/Rac)-activated kinase 2 (PAK2)|
|The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. [provided by RefSeq]. |
MAPK signaling pathway
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Western blot - PAK2 (phospho S20) antibody [EPR658(2)]; All lanes : Anti-PAK2 (phospho S20) antibody [EPR658(2)] at 1/20000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HeLa cell lysate treated with calyculin A.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/1000 dilution.Predicted band size : 58 kDa.Observed band size : 58 kDa.