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Home Antibody All anti-PAFAH1B1 antibodies

Anti-PAFAH1B1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302796
  • Goat Polyclonal Antibody against PAFAH1B1
100ug 325 3-7 Days
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WB(1)

OriGene Data

Immunogen Peptide with sequence TGSVDQTVKVWECR, from the C Terminus of the protein sequence according to NP_000421.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Rat. Expected from seq similarity: Human, Mouse, Rat, Dog, Pig, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameMus musculus platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 (Pafah1b1), transcript variant 1
Alternative NameLIS-1; Lis1; Mdsh; MMS10-U; Ms10u; Pafaha
Database LinkNP_038653
Entrez Gene 5048 Human
Entrez Gene 18472 Mouse
Entrez Gene 83572 Rat
Entrez Gene 480656 Dog
FunctionPAFAH1B1 was identified as encoding a gene that when mutated or lost caused the lissencephaly associated with Miller-Dieker lissencephaly syndrome. PAFAH1B1 encodes the non-catalytic alpha subunit of the intracellular Ib isoform of platelet-activating factor acteylhydrolase, a heterotrimeric enzyme that specifically catalyzes the removal of the acetyl group at the SN-2 position of platelet-activating factor (identified as 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine). Two other isoforms of intracellular platelet-activating factor acetylhydrolase exist: one composed of multiple subunits, the other, a single subunit. In addition, a single-subunit isoform of this enzyme is found in serum. [provided by RefSeq].
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302796 staining (2µg/ml) of NIH-3T3 lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

 

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