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Home Antibody All anti-P2RX7 antibodies

Anti-P2RX7 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305642
  • Goat Anti-P2RX7 / P2X7 receptor Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400907) , 20ug
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenPeptide with sequence YETNKVTRIQSMNY-C, from the N-Terminus of the protein sequence according to NP_002553.2.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Mouse, Rat, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1-3ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens purinergic receptor P2X, ligand-gated ion channel, 7 (P2RX7), transcript variant 1
Alternative NameP2X7
Database LinkNP_002553
FunctionThe product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq].
Related Pathway

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WB Image
TA305642 staining (0.3ug/ml) of Human Brain (Frontal Cortex) lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

 

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